Madelaine works in a collaborative effort of the Bijlsma and the Van Laarhoven labs at the AMC and the Van Eijck group at the EMC, Rotterdam. Her research activities include:
- establish organoid models for metastatic PDAC
- employ organoid technology to predict response to systemic treatments
- correlate gene expression-based subclasses of PDAC to organoid responses to currently applicable chemotherapeutics.
- identify and develop effective novel treatments based on response data and molecular information.
Madelaine’s work is supported by Stichting Overleven met Alveesklierkanker.